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Article

The fog-3 gene and regulation of cell fate in the germ line of Caenorhabditis elegans.

Genetics - 1 Feb 1995

Ellis R E, Kimble J

Abstract excerpt

In the nematode Caenorhabditis elegans, germ cells normally adopt one of three fates: mitosis, spermatogenesis or oogenesis. We have identified and characterized the gene fog-3, which is required for germ cells to differentiate as sperm rather than as oocytes. Analysis of double mutants suggests that fog-3 is absolutely required for spermatogenesis and acts at the end of the regulatory hierarchy controlling sex...

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Identifiers

PMID: 7713418
DOI: 10.1093/genetics/139.2.561
PMCID: PMC1206367

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