Article
The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis
2020-02-11
Abstract excerpt
<h4>Background</h4> In the past 15 years, numerous studies have described aberrant DNA methylation of imprinted genes (e.g. MEST and H19 ) in sperm of infertile patients, but the prevalence and genomic extent of abnormal methylation patterns have remained unknown. <h4>Results</h4> Using deep bisulfite sequencing (DBS), we screened swim-up sperm samples from 40 normozoospermic and 93 oligoasthenoteratozoosperm...
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Identifiers and source
- Literature Corpus work
- c7376a4a-12f4-5ac9-ad5d-b7824661ea8f
- DOI
- 10.1101/2020.02.10.941724