Article

Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls

2019-11-29

Abstract excerpt

<h4>Background</h4> Diagnostic categories within the psychosis spectrum are widely used in clinical practice, however psychosis may occur on a continuum. Therefore, we explored whether the continuous distribution of psychotic symptoms across categories is a function of genetic as well as environmental risk factors, such as polygenic risk scores (PRSs) and cannabis use. <h4>Methods</h4> As part of the EU-GEI study,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c731e8f1-4a34-5e99-98d8-77324f609775
DOI: 10.1101/19013284

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controlsDOI 10.1101/19013284Read

Cannabis-associated symptom profiles in patients with first episode psychosis and population controlsSemantic proximity Read

The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.Semantic proximity Read

Independent contribution of polygenic risk for schizophrenia and cannabis use in predicting psychotic-like experiences in young adulthood: testing gene × environment moderation and mediationSemantic proximity Read

Associations Between Cannabis Use, Polygenic Liability for Schizophrenia, and Cannabis-related Experiences in a Sample of Cannabis Users.Semantic proximity Read

Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study.Semantic proximity Read

The impact of schizophrenia genetic load and heavy cannabis use on the risk of psychotic disorder in the EU-GEI case-control and UK Biobank studies.Semantic proximity Read

The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study.Semantic proximity Read

Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophreniaSemantic proximity Read

Heritability estimates for psychotic symptom dimensions in twins with psychotic disorders.Semantic proximity Read

A systematic review of genome-wide research on psychotic experiences and negative symptom traits: new revelations and implications for psychiatry.Semantic proximity Read

Use of multiple Polygenic Risk Scores for distinguishing Schizophrenia-spectrum disorder and Affective psychosis categories; the EUGEI studySemantic proximity Read

Schizophrenia polygenic risk score and 20-year course of illness in psychotic disorders.Semantic proximity Read