Article
Associations Between Cannabis Use, Polygenic Liability for Schizophrenia, and Cannabis-related Experiences in a Sample of Cannabis Users.
Schizophrenia bulletin - 3 May 2023
Johnson Emma C, Colbert Sarah M C, Jeffries Paul W, Tillman Rebecca, Bigdeli Tim B, Karcher Nicole R, Chan Grace, Kuperman Samuel, Meyers Jacquelyn L, Nurnberger John I, Plawecki Martin H, Degenhardt Louisa, Martin Nicholas G, Kamarajan Chella, Schuckit Marc A, Murray Robin M, Dick Danielle M, Edenberg Howard J, D'Souza Deepak Cyril, Di Forti Marta, Porjesz Bernice, Nelson Elliot C, Agrawal Arpana
Abstract excerpt
BACKGROUND AND HYPOTHESIS: Risk for cannabis use and schizophrenia is influenced in part by genetic factors, and there is evidence that genetic risk for schizophrenia is associated with subclinical psychotic-like experiences (PLEs). Few studies to date have examined whether genetic risk for schizophrenia is associated with cannabis-related PLEs. STUDY DESIGN: We tested whether measures of cannabis involvement and...
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