Article

The polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer

2022-12-07

Abstract excerpt

<title>Abstract</title><p><bold>Background:</bold>Diabetes is significantly associated with increased cancer risk, with several studies reporting hyperglycemia as a primary oncogenic stimulant. Glucose metabolism is linked to numerous metabolic pathways, making it difficult to specify the mechanisms underlying hyperglycemia-induced cancer progression. Here, we focused on the polyol pathway, which is dramatically a...

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Literature Corpus work: c6c89d25-d7d4-59f5-96a1-5c7eaf6373da
DOI: 10.21203/rs.3.rs-2345829/v1

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