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Transcriptome and histone epigenome of <i>Plasmodium vivax</i> salivary-gland sporozoites point to tight regulatory control and potential mechanisms for liver-stage differentiation

2017-06-07

Abstract excerpt

<h4>ABSTRACT</h4> Plasmodium vivax is the key obstacle to malaria elimination in Asia and Latin America, largely attributed to its ability to form resilient hypnozoites (sleeper-cells) in the host liver that escape treatment and cause relapsing infections. The decision to form hypnozoites is made early in the liver infection and may already be set in sporozoites prior to invasion. To better understand these early...

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Literature Corpus work
469a38fc-0c97-5f1d-8d01-532354495e15
DOI
10.1101/145250
Open publication

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