Article

Global gene expression of human malaria parasite liver stages throughout intrahepatocytic development

2023-01-05

Abstract excerpt

<h4>ABSTRACT</h4> Plasmodium falciparum ( Pf ) is causing the greatest malaria burden, yet the liver stages (LS) of this most important parasite species have remained poorly studied. Here, we used a human liver-chimeric mouse model in combination with a novel fluorescent Pf NF54 parasite line ( Pf NF54 csp GFP) to isolate Pf LS-infected hepatocytes and generate transcriptomes that cover the major LS developm...

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Literature Corpus work: 2c5966bc-c9e7-57a7-839e-76db1dff5412
DOI: 10.1101/2023.01.05.522945

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