Article

Lovastatin Inhibits EMT and Metastasis of Triple-Negative Breast Cancer Stem Cells Through Dysregulation of Cytoskeleton-Associated Proteins

2021-01-19

Abstract excerpt

<title>Abstract</title> <p>Background Triple-negative breast cancer (TNBC) is more aggressive and has poorer prognosis compared to other subtypes of breast cancer. Epithelial-to-mesenchymal transition (EMT) is a process in which epithelial cells transform into mesenchymal-like cells capable of migration, invasion, and metastasis. Recently, we have demonstrated that lovastatin, a 3-hydroxy-3-methylglutaryl-coenzy...

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Literature Corpus work: c62e44c0-e602-57c8-9646-4e51a81bbb15
DOI: 10.21203/rs.3.rs-147845/v1

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