Article

Acetyl-cinobufagin Suppresses Triple Negative Breast Cancer Progression by Inhibiting the STAT3 Pathway

2021-12-20

Abstract excerpt

<h4>Background: </h4> The incidence of breast cancer (BC) worldwide has increased substantially in recent years. Epithelial-mesenchymal transition (EMT) refers to a crucial event impacting tumor heterogeneity. Although cinobufagin acts as an effective anticancer agent, the clinical use of cinobufagin is limited due to its strong toxicity. Acetyl-cinobufagin, a pre-drug of cinobufagin, was developed and prepared wi...

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Literature Corpus work: 46e248a1-4e7a-5afa-8967-b7ee030b84c7
DOI: 10.21203/rs.3.rs-1173263/v1

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