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Signaling pathways essential for triple-negative breast cancer stem-like cells

8 Dec 2020

Abstract excerpt

Since the discovery of breast cancer stem cells (CSCs), a significant effort has been made to identify and characterize these cells. It is a generally believe that CSCs play an important role in cancer initiation, therapy resistance, and progression of triple-negative breast cancer (TNBC), an aggressive breast cancer subtype with poor prognosis. Thus, therapies targeting these cells would be a valuable addition...

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PMID: 33211379
DOI: 10.1002/stem.3301

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