Back to search

Article

iPS-derived exosomes alleviate endothelial cell apoptosis and inflammation in Kawasaki disease through endogenous hsa-miR-1976 binding to CD40

2024-12-13

Abstract excerpt

<h4>Background: </h4> and Purpose: Kawasaki disease (KD) is an acute, self-limiting vasculitis with an elusive etiology and can cause vascular endothelial injury. Exosomes derived from induced pluripotent stem cells (iPS-EXO) can exhibit anti-inflammatory, anti-oxidation, and anti-apoptosis properties. The objective of study is to explore the therapeutic effects of iPS-EXO on KD, and try to illuminate the underlyi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4bab0762-f29b-505f-98ca-b670b5fbeccd
DOI
10.22541/au.173408996.67515247/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
iPS-derived exosomes alleviate endothelial cell apoptosis and inflammation in Kawasaki disease through endogenous hsa-miR-1976 binding to CD40DOI 10.22541/au.173408996.67515247/v1
Hesperidin alleviates endothelial cell inflammation and apoptosis of Kawasaki disease through inhibiting the TLR4/IĸBα/NF-ĸB pathwaySemantic proximity
Circulating miR-10b-5p drives Kawasaki vasculitis through endothelial reprogramming and nominates CXCL8 as an early diagnostic biomarkerSemantic proximity
Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki diseaseSemantic proximity
Single-cell RNA-seq reveals altered plasma cell subsets and decreased cytotoxicity of NK cells in patients with Kawasaki diseaseSemantic proximity
Dental pulp mesenchymal stem cell-derived exosomes inhibit neuroinflammation and microglial pyroptosis in subarachnoid hemorrhage via the miRNA-197-3p/Foxo3 axisSemantic proximity
SHEP1 alleviates cardiac ischemia reperfusion injury via targeting G3BP1 to regulate macrophage infiltration and inflammationSemantic proximity
Expression Profile Analysis of Differentially Expressed Genes in Human Coronary Artery Endothelial Cells Induced by Serum From Kawasaki Disease: A Preliminary StudySemantic proximity
Reversal of the Inflammatory Responses in Fabry Patient iPSC-Derived Cardiovascular Endothelial Cells by CRISPR/Cas9-Corrected Mutation.Semantic proximity
Delineation of Single-cell Altas Provides New Insights for Development of Coronary Artery Lesions in Kawasaki Disease: Bad and Good Signaling MoleculesSemantic proximity
Identification and validation of autophagy-related genes in Kawasaki diseaseSemantic proximity
Mechanistic insights into adipose-derived stem cells and exosomes in ischemia-reperfusion injury repair: from shared pathways to organ-specific therapeuticsSemantic proximity
Identification and validation of autophagy-related genes in Kawasaki diseaseSemantic proximity
Select a neighboring publication to make it the new centre.