Article

Platelet-derived small extracellular vesicles (PDsEVs) sequencing unveils MEF2B as potential target in atherosclerosis-related diseases

2026-06-13

Abstract excerpt

<title>Abstract</title> <p>Background Given the escalating global burden of cardiovascular diseases (CVDs), atherosclerosis remains a central focus of research. This chronic disorder is characterized by endothelial dysfunction, lipid dysregulation, inflammation, and a complex interplay of genetic factors. Beyond their canonical role in hemostasis, activated platelets may contribute to vascular pathology through...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d8e9cd32-a703-5813-acd6-77cdcced46de
DOI: 10.21203/rs.3.rs-9399097/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Platelet-derived small extracellular vesicles (PDsEVs) sequencing unveils MEF2B as potential target in atherosclerosis-related diseasesDOI 10.21203/rs.3.rs-9399097/v1Read

The Dual Role of Extracellular Vesicles in Atherosclerosis: From Pathogenic Mediators to Translational Tools in Diagnosis and Targeted TherapySemantic proximity Read

Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosisSemantic proximity Read

Carotid Plaque‐Derived Small Extracellular Vesicles Mediate Atherosclerosis and Correlate With Plaque VulnerabilitySemantic proximity Read

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque responsesSemantic proximity Read

Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wallSemantic proximity Read

Exosomes: mediators regulating the phenotypic transition of vascular smooth muscle cells in atherosclerosis.Semantic proximity Read

Conserved and Divergent Modulation of Calcification in Atherosclerosis and Aortic Valve Disease by Tissue Extracellular VesiclesSemantic proximity Read

Extracellular vesicles from patients with coronary artery disease (CAD) demonstrate enhanced pro-coagulatory activitySemantic proximity Read

Emerging understandings of the role of exosomes in atherosclerosisSemantic proximity Read

Engineering extracellular vesicles for targeted therapeutics in cardiovascular diseaseSemantic proximity Read

Isolation and Characterization of Human Adipocyte-derived Extracellular Vesicles Using Filtration and UltracentrifugationSemantic proximity Read

Extracellular vesicles: new players in regulating vascular barrier functionSemantic proximity Read