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Article

Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management.

ACS nano - 22 Jul 2025

Dong Xiaoyan, Suo Yaoyu, Yu Jie, Yu Feifei, Li Feng, Zheng Judun, Li Guizhong, Ma Shengchao, Hao Yinju, Zhang Huiping, Liu Bin, Jiang Yideng

Abstract excerpt

Atherosclerosis, characterized by dyslipidemia and severe inflammation, has become the main cause of cardiovascular disease. However, accurately and efficiently regulating lipid metabolism and relieving inflammation is a great challenge. Herein, we design a plaque/macrophage dual-targeting programmed atherosclerosis management strategy for synchronously regulating lipid metabolism and the macrophage phenotype....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40637034
DOI: 10.1021/acsnano.5c00216
PMCID: PMC12291585

Genes

CD36

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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