Article

Extensive DNA methylome rearrangement during early lamprey embryogenesis

2023-05-25

Abstract excerpt

<h4>ABSTRACT</h4> DNA methylation (5-methylcytosine, 5mC) is a repressive gene regulatory mark widespread in vertebrate genomes, yet the developmental dynamics in which 5mC patterns are established vary across species. While mammals undergo two rounds of global 5mC erasure, the zebrafish genome exhibits localized maternal-to-paternal 5mC remodeling, in which the sperm epigenome is inherited in the early embryo. T...

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Literature Corpus work: c620fae8-7e1f-53d7-a908-6fc896a19c8f
DOI: 10.1101/2023.05.25.542242

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