Article
An oxadiazole-based compound potentiates anti-tuberculosis treatment by increasing host resistance via zinc poisoning
2023-07-21
Abstract excerpt
Anti-tuberculosis drugs, mostly developed over 60 years ago, combined with a poorly effective vaccine, have failed to eradicate tuberculosis. More worryingly, multi-resistant strains of Mycobacterium tuberculosis are constantly emerging. Innovative strategies are thus urgently needed to improve tuberculosis treatment. Recently, host-directed therapy has emerged as a promising strategy to be used in adjunct with e...
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Identifiers and source
- Literature Corpus work
- c595cb14-3100-5449-a1c6-69950d0495d4
- DOI
- 10.1101/2023.07.21.549986