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Enhanced expression of Dystrophin, IGF-1, CD44 and MYH3 in plasma and skeletal muscles including Diaphragm of <i>mdx</i> mice after oral administration of Neu REFIX Beta 1,3-1,6 glucan

2023-06-07

Abstract excerpt

<h4>Introduction</h4> Duchenne muscular dystrophy (DMD) is a rare genetic disease, causing muscle degeneration due to lack of dystrophin with inadequate muscle regeneration culminating in muscle dysfunction. The N-163 strain of Aureobasidium Pullulans produced Beta-1,3-1,6-glucan (Neu REFIX) reported to be safe with anti-inflammatory and anti-fibrotic efficacy earlier, herein we evaluated its effects on muscle r...

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Literature Corpus work
c591a05c-39a3-5668-ab83-f2ca80d2f54c
DOI
10.1101/2023.06.06.543858
Open publication

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Enhanced expression of Dystrophin, IGF-1, CD44 and MYH3 in plasma and skeletal muscles including Diaphragm of <i>mdx</i> mice after oral administration of Neu REFIX Beta 1,3-1,6 glucanDOI 10.1101/2023.06.06.543858
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