Article

Biomarkers for Duchenne muscular dystrophy progression: impact of age in the mdx tongue spared muscle

2023-06-13

Abstract excerpt

<h4>Background: </h4> Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy without an effective treatment, caused by mutations in the DMD gene, leading to the absence of dystrophin. DMD results in muscle weakness, loss of ambulation and death at an early age. Metabolomics studies in mdx mice, the most used model for DMD, reveal changes in metabolites associated with muscle degeneration and agin...

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Literature Corpus work: 32d5e6ee-d8fb-537f-9325-9ddecebe5856
DOI: 10.21203/rs.3.rs-3038923/v1

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