Article

Therapeutic Effect of a Recombinant Human Fibronectin Construct in Skeletal Muscle Repair and Oxidative Stress

2025-07-17

Abstract excerpt

Aging mice experience a depletion of muscle extracellular matrix fibronectin (FN). Therefore, enhancing FN expression in the aging tissue microenvironment may be able to maintain satellite cell function and facilitate the repair of damaged skeletal muscle. Herein, we have used molecular dynamics (MD) simulations to select FN functional domains which were combined into a single construct, rhFN-NM (recombinant human...

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Literature Corpus work: feb025db-aeaa-5da4-8c66-45c25b9fdca6
DOI: 10.20944/preprints202507.1441.v1

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