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Galectin-3 and <i>N</i> -acetylglucosamine promote myogenesis and improve skeletal muscle function in the <i>mdx</i> model of Duchenne muscular dystrophy

2017-10-16

Abstract excerpt

The muscle membrane, sarcolemma, must be firmly attached to the basal lamina. The failure of proper attachment results in muscle injury, which is the underlying cause of Duchenne muscular dystrophy (DMD), where mutations in the dystrophin gene disrupts the firm adhesion. In DMD patients, even moderate contraction causes damage, leading to progressive muscle degeneration. The damaged muscles are repaired through my...

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Literature Corpus work
571f5e12-0b27-519d-aec5-77df18d1bdd8
DOI
10.1101/203653
Open publication

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