Article

Efficacy of N-163 beta-glucan in beneficially improving biomarkers of relevance to muscle function in patients with muscular dystrophies in a pilot clinical study

2023-07-24

Abstract excerpt

<h4>Background:</h4> Muscular dystrophies other than Duchenne muscular dystrophy (DMD) are genetic diseases characterized by increasing muscle weakness, loss of ambulation, and ultimately cardiac and respiratory failure. There are currently no effective therapeutics available. Having demonstrated the efficacy of a N-163 strain of Aureobasidium Pullulans (Neu-REFIX) produced B-1, 3-1,6-Glucan in pre-clinical and cl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8f12d656-a1c7-5317-a3c2-e246b8d94773
DOI: 10.1101/2023.07.20.23292982

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Efficacy of N-163 beta-glucan in beneficially improving biomarkers of relevance to muscle function in patients with muscular dystrophies in a pilot clinical studyDOI 10.1101/2023.07.20.23292982Read

Efficacy of N-163 strain of<i>Aureobasidium pullulans</i>-produced beta-glucan in improving muscle strength and function in patients with Duchenne muscular dystrophy; Results of a 6-month non-randomised open-label linear clinical trialSemantic proximity Read

Enhanced expression of Dystrophin, IGF-1, CD44 and MYH3 in plasma and skeletal muscles including Diaphragm of <i>mdx</i> mice after oral administration of Neu REFIX Beta 1,3-1,6 glucanSemantic proximity Read

Resolution of fibrosis in mdx dystrophic mouse after oral consumption of N-163 strain of <i>Aureobasidium pullulans</i> produced biological response modifier β-glucan (BRMG)Semantic proximity Read

Reduction in myocardial fibrosis in MDX mice on oral consumption of <i>Aureobasidium Pullulans</i> produced Neu REFIX Beta-glucans; holds potential as an adjuvant in managing post-transplantation organ fibrosisSemantic proximity Read

Nutritional intervention with cyanidin hinders the progression of muscular dystrophy.Semantic proximity Read

Nutrition Considerations in Duchenne Muscular DystrophySemantic proximity Read

Hydrogen-Oxygen Nanobubble Therapy as a Complementary Approach in a Female Patient with Duchenne Muscular Dystrophy (DMD): A Case ReportSemantic proximity Read

A Potential Beta-hydroxybutyrate Therapy for Duchenne Muscular Dystrophy in Disease ModelsSemantic proximity Read

6′-Sialyllactose Enhances Exercise Performance via Increased Muscle Mass and StrengthSemantic proximity Read

Effects of functional β-glucan on proliferation, differentiation, metabolism and its anti-fibrosis properties in muscle cells.Semantic proximity Read

Casein Protein Hydrolysate Fed Human Serum From Older Adults Regulates In Vitro Muscle Protein Synthesis, Muscle Protein Breakdown and Myotube GrowthSemantic proximity Read

Results of a two-year pilot study of clinical outcome measures in collagen VI- and laminin alpha2-related congenital muscular dystrophies.Semantic proximity Read