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The role of melatonin deficiency induced by pinealectomy on motor activity and anxiety responses in young adult, middle-aged and old rats

2023-09-13

Abstract excerpt

<h4>Background: </h4> Aging affects anxiety levels in rats while the pineal gland, via its hormone melatonin, could modulate their inherited life “clock.” The present study aimed to explore the impact of plasma melatonin deficiency on anxiety responses and the possible involvement of the hypothalamic-pituitary-adrenocortical (HPA) axis and heat shock proteins (Hsp) 70 and 90 in the frontal cortex (FC) and the hipp...

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Literature Corpus work
c56d9d85-fcf2-5d33-a2be-8dbde9a2620a
DOI
10.21203/rs.3.rs-3338657/v1
Open publication

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