Article

Structural Mechanisms of Actin Isoforms

2022-08-01

Abstract excerpt

Actin isoforms organize into distinct networks that are essential for the normal function of eukaryotic cells. Despite a high level of sequence and structure conservation, subtle changes in their design principles determine the interaction with myosin motors and actin-binding proteins. The functional diversity is further increased by posttranslational modifications (PTMs). Therefore, identifying how the structure...

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Literature Corpus work: c5d7c222-cf31-59b8-844a-3e5ac653ddf9
DOI: 10.1101/2022.08.01.502282

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