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Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

2019-12-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> The thickness of the cerebral cortical sheet and its surface area are highly heritable traits thought to have largely distinct polygenic architectures. Despite large-scale efforts, the majority of their genetic determinants remains unknown. Our ability to identify causal genetic variants can be improved by employing better delineated, less noisy brain measures that better...

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Literature Corpus work
b7d1dcc6-1e8d-5b57-8db9-c395e15df43a
DOI
10.1101/868307
Open publication

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Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface areaDOI 10.1101/868307
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