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Colistin resistance-mediated lipopolysaccharide modification in <i>Klebsiella pneumoniae</i> modulates host inflammatory response

2026-07-31

Abstract excerpt

Resistance to the polymyxin antimicrobial colistin in Gram-negative bacteria is associated with a modification of the immunogenic lipid A moiety of the lipopolysaccharide (LPS). Chromosomal and plasmid-borne colistin resistance results in the addition of L-Ara4N and pEtN groups to lipopolysaccharide (LPS), respectively. Here, using THP-1 cells, we studied the impact of different LPS modifications of Klebsiella pn...

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Literature Corpus work
c548951a-bbbf-5f31-96a3-dd9d027fd984
DOI
10.64898/2026.07.30.741922
Open publication

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Colistin resistance-mediated lipopolysaccharide modification in <i>Klebsiella pneumoniae</i> modulates host inflammatory responseDOI 10.64898/2026.07.30.741922
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