Article
Proteomic Changes of Klebsiella pneumoniae in Response to Colistin Treatment and crrB Mutation-Mediated Colistin Resistance.
Antimicrobial agents and chemotherapy - 21 May 2020
Sun Lang, Rasmussen Pernille Kronholm, Bai Yinlei, Chen Xiulan, Cai Tanxi, Wang Jifeng, Guo Xiaojing, Xie Zhensheng, Ding Xiang, Niu Lili, Zhu Nali, You Xuefu, Kirpekar Finn, Yang Fuquan
Abstract excerpt
Polymyxins are increasingly used as the critical last-resort therapeutic options for multidrug-resistant Gram-negative bacteria. Unfortunately, polymyxin resistance has increased gradually over the past few years. Although studies on polymyxin mechanisms are expanding, systemwide analyses of the underlying mechanism for polymyxin resistance and stress response are still lacking. To understand how Klebsiella...
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