Article
Molecular Mechanisms of Colistin Resistance in Klebsiella pneumoniae Causing Bacteremia from India—A First Report
9 Jan 2017
Abstract excerpt
Background: Colistin has long been the drug of last resort in the treatment of carbapenem resistant Klebsiella pneumoniae. Carbapenem resistance in K.pneumoniae is increasing and is as high as 44% in India. The rise in rates of carbapenem resistance has resulted in increased use of colistin which has led to the emergence of colistin resistance. Colistin resistance is mainly mediated by alteration in the...