Article

Single-cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus

2025-05-28

Abstract excerpt

<h4>Objective</h4> Rituximab, a CD20 + B cell depletion therapy, is frequently used in the treatment of systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation. <h4>Methods</h4> In this study, we conducted longitudinal single-cell profiling of nine SLE patients treated wit...

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Literature Corpus work: c4f33878-eb94-5ffa-a6dd-5c3601c94964
DOI: 10.1101/2025.05.27.25328230

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