Article

RNA-seq analysis of skeletal muscle in motor neurone disease cases and controls

2023-03-19

Abstract excerpt

<h4>Background</h4> Amyotrophic lateral sclerosis (ALS), the most predominant form of Motor Neuron Disease (MND), is a progressive and fatal neurodegenerative condition that spreads throughout the neuromotor system by afflicting upper and lower motor neurons. Lower motor neurons project from the central nervous system and innervate muscle fibres at motor endplates, which degrade over the course of the disease lead...

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Literature Corpus work: c4e6dda4-e920-5b69-8806-21d0c93081e7
DOI: 10.1101/2023.03.13.23287229

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