Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

7 Jan 2025

Abstract excerpt

Blood-based biomarkers for motor neuron disease are needed for better diagnosis, progression prediction, and clinical trial monitoring. We used whole blood-derived total RNA and performed whole transcriptome analysis to compare the gene expression profiles in (motor neurone disease) MND patients to the control subjects. We compared 42 MND patients to 42 aged and sex-matched healthy controls and described the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Neurogenetic and Muscular Disorders Research
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39844875
DOI: 10.3389/ebm.2024.10401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signaturesPMID 39844875Read ↗

Whole blood transcriptome profile identifies motor neurone disease (MND) RNA biomarker signaturesSemantic proximity Read ↗

Blood RNA transcripts reveal similar and differential alterations in fundamental cellular processes in Alzheimer's disease and other neurodegenerative diseasesSemantic proximity Read ↗

RNA-seq analysis of skeletal muscle in motor neurone disease cases and controlsSemantic proximity Read ↗

Gene Expression Signatures of Sporadic ALS Motor Neuron PopulationsSemantic proximity Read ↗

A Blood Transcriptomic Resource for ALS Highlights Disease-Associated Signatures and Alternative Splicing EventsSemantic proximity Read ↗

Transcriptional Analysis of Nuclear-Encoded Mitochondrial Genes in Eight Neurodegenerative Disorders: The Analysis of Seven Diseases in Reference to Friedreich’s AtaxiaSemantic proximity Read ↗

Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALSSemantic proximity Read ↗

Identification of molecular signatures and pathways common to blood cells and brain tissue of amyotrophic lateral sclerosis patientsSemantic proximity Read ↗

Transcriptional Signatures of Synaptic Vesicle Genes Define Myotonic Dystrophy Type I NeurodegenerationSemantic proximity Read ↗

RNA sequencing of whole blood reveals early alterations in immune cells and gene expression in Parkinson’s diseaseSemantic proximity Read ↗

Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALSSemantic proximity Read ↗

Whole blood transcriptome analysis in amyotrophic lateral sclerosis: A biomarker studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.