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Article

Biomarkers and immunoprofiles associated with fetal abnormalities of ZIKV-positive pregnancies

1 Nov 2018

Abstract excerpt

BACKGROUND: An intricate fetal-maternal immune crosstalk during pregnancy is essential for a healthy birth. Hence, the infection-induced alterations of maternal immunity often lead to adverse outcomes for mother and/or child. The emergence of Zika virus (ZIKV) infection in pregnant women has been associated with more than 3,000 cases of microcephaly and nervous system malformations. METHODS: To explore the...

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PMID: 30385728
DOI: 10.1172/jci.insight.124152

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