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IPF Disorder-Weighted PPI Explorer: A Network-Based Computational Framework for Identifying Vulnerable Molecular Targets in Idiopathic Pulmonary Fibrosis

2025-12-29

Abstract excerpt

<title>Abstract</title> <p>Idiopathic Pulmonary Fibrosis (IPF) is a progressive interstitial lung disease characterized by irreversible fibrotic remodeling and high mortality. While numerous molecular factors have been implicated, the systems-level mechanisms that govern network vulnerability in IPF remain poorly understood. In particular, conventional bioinformatics approaches often emphasize gene expression or...

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Literature Corpus work
c4d3ad5e-2056-5214-a1cc-d2c463fcc15a
DOI
10.21203/rs.3.rs-8432450/v1
Open publication

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IPF Disorder-Weighted PPI Explorer: A Network-Based Computational Framework for Identifying Vulnerable Molecular Targets in Idiopathic Pulmonary FibrosisDOI 10.21203/rs.3.rs-8432450/v1
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