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Harnessing gene-gene interactions via an RNA-Sequencing network analysis framework improves precision medicine prediction in rheumatoid arthritis

2021-12-09

Abstract excerpt

<h4>ABSTRACT</h4> The study of gene-gene interactions in RNA-Sequencing (RNA-Seq) data has traditionally been hard owing the large number of genes detectable by Next-Generation Sequencing (NGS). However, differential gene-gene pairs can inform our understanding of biological processes and yield improved prediction models. Here, we utilised four well curated pathway repositories obtaining 10,537 experimentally eva...

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Literature Corpus work
c4cc57e2-0f22-535f-93ae-3b9412c58a92
DOI
10.1101/2021.12.08.471133
Open publication

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Harnessing gene-gene interactions via an RNA-Sequencing network analysis framework improves precision medicine prediction in rheumatoid arthritisDOI 10.1101/2021.12.08.471133
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