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Article

Deep phenotyping of synovial molecular signatures by integrative systems analysis in rheumatoid arthritis.

Rheumatology (Oxford, England) - 1 Jul 2021

Jung Seung Min, Park Kyung-Su, Kim Ki-Jo

Abstract excerpt

OBJECTIVE: RA encompasses a complex, heterogeneous and dynamic group of diseases arising from molecular and cellular perturbations of synovial tissues. The aim of this study was to decipher this complexity using an integrative systems approach and provide novel insights for designing stratified treatments. METHODS: An RNA sequencing dataset of synovial tissues from 152 RA patients and 28 normal controls was...

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PMID: 33230538
DOI: 10.1093/rheumatology/keaa751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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