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Article

Pax6 transcription factor is required for the interkinetic nuclear movement of neuroepithelial cells.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2007

Tamai Hiroshi, Shinohara Hiroshi, Miyata Takaki, Saito Kanako, Nishizawa Yuji, Nomura Tadashi, Osumi Noriko

Abstract excerpt

The mammalian cerebral cortex develops from proliferative neuroepithelial cells that exhibit a cell cycle-dependent nuclear movement (interkinetic nuclear migration; INM). Pax6 transcription factor plays pivotal roles in various aspects of corticogenesis. From live observation using cultured cortical slices from the Pax6 mutant rat, we identified the premature descent of S phase cells, the unsteady ascent or...

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Identifiers

PMID: 17825043
DOI: 10.1111/j.1365-2443.2007.01113.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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