Article

GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomas

2024-12-06

Abstract excerpt

Gap junctions are specialized intercellular connections that directly connect the cytoplasm of two cells via protein structure called connexins. Despite extensive research on many cell surface proteins, Gap junction proteins are understudied in cancer. In this study, we used TCGA data to identify genetic and epigenetic changes associated with Gap junction proteins. The analysis identified GJB3 as a key gene with d...

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Literature Corpus work: c4b62ed4-7979-5a61-b8f7-2a4b2214dd6c
DOI: 10.1101/2024.12.03.626548

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GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomasDOI 10.1101/2024.12.03.626548Read

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