Article

Transcriptome Profiling Unveils GAP43 Regulates ABC Transporters and EIF2 Signaling in Colorectal Cancer Cells

2020-09-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>The growth- and plasticity-associated protein-43 (GAP43) is biasedly expressed in indigestive system and nervous system. Recent study has shown that GAP43 is responsible for the development of neuronal growth and axonal regeneration in normal nervous tissue, while serves as a specific biomarker of relapsed or refractory neuroblastoma. However, its expression patte...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c40d712b-dbf9-5631-882d-b8e56df38ee0
DOI: 10.21203/rs.3.rs-74222/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptome Profiling Unveils GAP43 Regulates ABC Transporters and EIF2 Signaling in Colorectal Cancer CellsDOI 10.21203/rs.3.rs-74222/v1Read

GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomasSemantic proximity Read

The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer CellsSemantic proximity Read

LncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer ProgressionSemantic proximity Read

miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1LSemantic proximity Read

Silencing GDI2 inhibits proliferation, migration and invasion of colorectal cancer through activation of p53 signaling pathwaySemantic proximity Read

A novel miR‐203‐DNMT3b‐ABCG2 regulatory pathway predisposing colorectal cancer developmentSemantic proximity Read

A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistanceSemantic proximity Read

Long non-coding RNA GAS5, by up-regulating PRC2 and targeting the promoter methylation of miR-424, suppresses multiple malignant phenotypes of glioma.Semantic proximity Read

Critical role of guanylate binding protein 5 in tumor immune microenvironment and predictive value of immunotherapy responseSemantic proximity Read

Pan-cancer analysis of the ion permeome reveals functional regulators of glioblastoma aggressionSemantic proximity Read

SLC43A3 Promotes Oncogenesis and Predicts Poor Prognosis in GliomaSemantic proximity Read

MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cellsSemantic proximity Read