Article

Genetic Susceptibility to Multiple Sclerosis: Interactions between Conserved Extended Haplotypes of the MHC and other Susceptibility Regions

2019-04-10

Abstract excerpt

<h4>OBJECTIVE</h4> To study the accumulation of MS-risk resulting from different combinations of MS-associated conserved-extended-haplotypes of the MHC and three non-MHC risk-loci nearby genes EOMES, ZFP36L1, CLEC16A. <h4>BACKGROUND</h4> Defining “genetic-susceptibility” as having a non-zero probability of developing MS, both theoretical considerations and epidemiological observations indicate that only 2.2–4.5%...

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Literature Corpus work: c497fac6-9320-5beb-bc02-264d8d4ea34e
DOI: 10.1101/603878

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