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Article

The epidemiology of multiple sclerosis: insights to a causal cascade.

Handbook of clinical neurology - 1 Jan 2016

Goodin D S

Abstract excerpt

MS-pathogenesis involves both genetic-susceptibility and environmental determinants. Three (or more) sequential environmental-factors are implicated. The first acts near birth, the second acts during childhood/adolescence, and the third acts subsequently. Two candidate factors (vitamin D deficiency and Epstein-Barr viral infection) seem particularly well-suited to the first two environmental-events but other...

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PMID: 27637959
DOI: 10.1016/B978-0-12-802973-2.00011-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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