Back to search

Article

The Nature of Genetic Susceptibility to Multiple Sclerosis

2020-08-14

Abstract excerpt

<h4>OBJECTIVE</h4> To explore the nature of MS-susceptibility and, by extension, other complex-genetic diseases. <h4>BACKGROUND</h4> Basic-epidemiological parameters of MS (e.g., prevalence, recurrence-risks for siblings and twins, time-dependent changes in sex-ratio, etc.) are well-established. Moreover, >200 genetic-loci are unequivocally MS-associated, especially the HLA-DRB1*15:01~HLA-DQB1*06:02~a1 haplotyp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7d0c9a59-a98d-5893-b69c-1dc97c4d77e8
DOI
10.1101/2020.08.13.249920
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Nature of Genetic Susceptibility to Multiple SclerosisDOI 10.1101/2020.08.13.249920
The nature of genetic and environmental susceptibility to multiple sclerosis.Semantic proximity
The nature of genetic susceptibility to multiple sclerosis: constraining the possibilities.Semantic proximity
Multiple Sclerosis: Exploring the Limits of Genetic and Environmental SusceptibilitySemantic proximity
Pathogenesis of Multiple Sclerosis: Genetic, Environmental, and Random MechanismsSemantic proximity
The epidemiology of multiple sclerosis: insights to a causal cascade.Semantic proximity
The genetic basis of multiple sclerosis: a model for MS susceptibility.Semantic proximity
The genetic and environmental bases of complex human-disease: extending the utility of twin-studies.Semantic proximity
The causal cascade to multiple sclerosis: a model for MS pathogenesis.Semantic proximity
Genetic Susceptibility to Multiple Sclerosis: Interactions between Conserved Extended Haplotypes of the MHC and other Susceptibility RegionsSemantic proximity
Multiple sclerosis: Exploring the limits and implications of genetic and environmental susceptibility.Semantic proximity
Pathogenesis of multiple sclerosis: genetic, environmental and random mechanisms.Semantic proximity
Genetic Risk in Multiple Sclerosis: Susceptibility, Modifiers and Unresolved QuestionsSemantic proximity
Select a neighboring publication to make it the new centre.