Article
The nature of genetic susceptibility to multiple sclerosis: constraining the possibilities.
BMC neurology - 27 Apr 2016
Goodin Douglas S
Abstract excerpt
BACKGROUND: Epidemiological observations regarding certain population-wide parameters (e.g., disease-prevalence, recurrence-risk in relatives, gender predilections, and the distribution of common genetic-variants) place important constraints on the possibilities for the genetic-basis underlying susceptibility to multiple sclerosis (MS). METHODS: Using very broad range-estimates for the different population-wide...
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