Article

Germline mutations directions are different between introns of the same gene: case study of the gene coding for amyloid-beta precursor protein

2022-08-16

Abstract excerpt

Amyloid-beta precursor protein (APP) is highly conserved in mammals. This feature allowed us to compare nucleotide usage biases in 4-fold degenerated sites along the length of its coding region for 146 species of mammals and birds in search of fragments with significant deviations. Even though cytosine usage has the highest value in 4-fold degenerated sites in APP coding region from all tested placental mammals, i...

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Literature Corpus work: c4937e6f-cbef-5234-8e50-24defe34521b
DOI: 10.21203/rs.3.rs-1840059/v2

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