Article

Germline-limited transposon remnants foster somatic genome diversification

2025-11-21

Abstract excerpt

<title>Abstract</title> <p>Transposable elements are mobile DNA sequences that propagate within genomes, often with deleterious effects on host fitness. Some organisms excise transposons from their somatic genomes via programmed DNA elimination yet paradoxically retain them in their germline. The evolutionary rationale for this selective retention remains poorly understood. To address this, we first set out to de...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 47d5d306-6e82-5b9e-a01b-f32b18493cd2
DOI: 10.21203/rs.3.rs-7978461/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Germline-limited transposon remnants foster somatic genome diversificationDOI 10.21203/rs.3.rs-7978461/v1Read

Germline-limited transposon remnants foster somatic genome diversificationSemantic proximity Read

Massive colonization of protein-coding exons by selfish genetic elements in <i>Paramecium</i> germline genomesSemantic proximity Read

Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia: a somatic view of the germline.Semantic proximity Read

The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of HelitronsSemantic proximity Read

Developmental timing of programmed DNA elimination in <i>Paramecium tetraurelia</i> recapitulates germline transposon evolutionary dynamicsSemantic proximity Read

Inter-generational nuclear crosstalk links the control of gene expression to programmed genome rearrangements during the <i>Paramecium</i> sexual cycleSemantic proximity Read

Remembrance of things past retrieved from the Paramecium genome.Semantic proximity Read

N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity Read

N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity Read

Enhanced plasticity of programmed DNA elimination boosts adaptive potential in suboptimal environmentsSemantic proximity Read

Comparative genomics reveals insight into the evolutionary origin of massively scrambled genomesSemantic proximity Read

Identification and analysis of functional associations among natural eukaryotic genome editing componentsSemantic proximity Read