Back to search

Article

Two paralogous PHD finger proteins participate in <i>Paramecium tetraurelia</i> ’s natural genome editing

2024-01-23

Abstract excerpt

The unicellular eukaryote Paramecium tetraurelia contains functionally distinct nuclei: germline micronuclei (MICs) and a somatic macronucleus (MAC). During sexual reproduction, the MIC genome is reorganized into a new MAC genome and the old MAC is lost. Almost 45,000 unique Internal Eliminated Sequences (IESs) distributed throughout the genome require precise excision to guarantee a functional new MAC genome. He...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5fd87937-66af-54a0-b92e-7d9d9438e7c3
DOI
10.1101/2024.01.23.576875
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Two paralogous PHD finger proteins participate in <i>Paramecium tetraurelia</i> ’s natural genome editingDOI 10.1101/2024.01.23.576875
Developmental timing of programmed DNA elimination in <i>Paramecium tetraurelia</i> recapitulates germline transposon evolutionary dynamicsSemantic proximity
Inter-generational nuclear crosstalk links the control of gene expression to programmed genome rearrangements during the <i>Paramecium</i> sexual cycleSemantic proximity
Massive colonization of protein-coding exons by selfish genetic elements in <i>Paramecium</i> germline genomesSemantic proximity
N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity
The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of HelitronsSemantic proximity
A development-specific POLX essential for programmed genome rearrangement in <i>Paramecium tetraurelia</i>Semantic proximity
The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in <i>Paramecium</i>Semantic proximity
N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity
Identification and analysis of functional associations among natural eukaryotic genome editing componentsSemantic proximity
Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia: a somatic view of the germline.Semantic proximity
The conjugation-specific Die5 protein is required for development of the somatic nucleus in both Paramecium and Tetrahymena.Semantic proximity
Remembrance of things past retrieved from the Paramecium genome.Semantic proximity
Select a neighboring publication to make it the new centre.