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Article

Development of an intestinal mucosa ex vivo co-culture model to study viral infections

30 Aug 2024

Abstract excerpt

ABSTRACT Studying viral infections necessitates well-designed cell culture models to deepen our understanding of diseases and develop effective treatments. In this study, we present a readily available ex vivo 3D co-culture model replicating the human intestinal mucosa. The model combines fully differentiated human intestinal epithelium (HIE) with human monocyte-derived macrophages (hMDMs) and faithfully mirrors...

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Share to Clostridium difficile and Clostridium perfringens research
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PMID: 39212448
DOI: 10.1128/jvi.00987-24

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