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Article

Robust and persistent SARS-CoV-2 infection in the human intestinal brush border expressing cells

1 Jan 2020

Abstract excerpt

Studies on patients with the coronavirus disease-2019 (COVID-19) have implicated that the gastrointestinal (GI) tract is a major site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We established a human GI tract cell line model highly permissive to SARS-CoV-2. These cells, C2BBe1 intestinal cells with a brush border having high levels of transmembrane serine protease 2 (TMPRSS2),...

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PMID: 32969768
DOI: 10.1080/22221751.2020.1827985

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