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Single-cell transcriptome analysis of the early immune response in the lymph nodes of <i>Borrelia burgdorferi</i> -infected mice

2023-11-29

Abstract excerpt

Lyme borreliosis is a disease caused by Borrelia burgdorferi sensu lato bacteria. Borrelia burgdorferi is known to induce prolonged extrafollicular immune responses and abnormal germinal center formation. However, the mechanism behind this is poorly understood. The extrafollicular response is characterized by strong plasmablast induction and by an IgM, IgG3, and IgG2b dominant antibody production. These antibodi...

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Literature Corpus work
c437876f-ca86-53d8-b497-8bacfd799a35
DOI
10.1101/2023.11.29.569164
Open publication

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Single-cell transcriptome analysis of the early immune response in the lymph nodes of <i>Borrelia burgdorferi</i> -infected miceDOI 10.1101/2023.11.29.569164
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