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The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic <i>Trypanosoma brucei</i> infection

2023-04-30

Abstract excerpt

The meningeal space is a critical brain structure providing immunosurveillance for the central nervous system, but the impact of infections on the meningeal immune landscape is far from being fully understood. The extracellular protozoan parasite Trypanosoma brucei , which causes Human African Trypanosomiasis (HAT) or sleeping sickness, accumulates in the meningeal spaces, ultimately inducing severe meningitis an...

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Literature Corpus work
32fb53fb-70ef-54b7-95ed-9aa8fdceed07
DOI
10.1101/2023.04.30.538710
Open publication

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