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Comparative transcriptome analysis of Peromyscus leucopus and C3H mice infected with the Lyme disease pathogen

11 Apr 2023

Abstract excerpt

Lyme disease (LD), the most prevalent tick-borne disease of humans in the Northern Hemisphere, is caused by the spirochetal bacterium of Borreliella burgdorferi (Bb) sensu lato complex. In nature, Bb spirochetes are continuously transmitted between Ixodes ticks and mammalian or avian reservoir hosts. Peromyscus leucopus mice are considered the primary mammalian reservoir of Bb in the United States. Earlier...

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PMID: 37113133
DOI: 10.3389/fcimb.2023.1115350

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