Article

Single cell transcriptomic landscapes of human liver organoids stratify models of non-alcoholic fatty liver disease

2022-07-20

Abstract excerpt

<h4>Summary</h4> Non-alcoholic fatty liver disease (NAFLD) is a rapidly growing cause of morbidity with few treatment options available. Thus, accurate in vitro systems to test new therapies are indispensable. Recently, human liver organoid (HLO) NAFLD models have emerged. However, a systematic evaluation of their translational potential is currently missing. Here, we develop a structured approach to evaluate NA...

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Literature Corpus work: c403ee38-3ed2-5cb4-97d1-c91b0798402a
DOI: 10.1101/2022.07.19.500693

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