Back to search

Article

Gene Panel Sequencing in a Chinese High-risk Breast Cancer Cohort

2019-01-07

Abstract excerpt

Currently, over 20 genes have been defined that can confer susceptibility for high-risk breast cancer. Although research has proved the utility of multiple-gene sequencing in the assessment of breast cancer risk, there is little data from China patients. Here, we use a multiple-gene sequencing panel to identify the variant spectrum in Chinese high-risk breast cancer subjects. A total of 829 Chinese high-risk breas...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c3f59bb2-f48a-5086-8f8f-43928f6b4bc0
DOI
10.1101/513317
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Gene Panel Sequencing in a Chinese High-risk Breast Cancer CohortDOI 10.1101/513317
Germline Mutations in 32 Cancer Susceptibility Genes by Next-Generation Sequencing among Breast Cancer Patients.Semantic proximity
Germline mutation landscape of Chinese patients with familial breast/ovarian cancer in a panel of 22 susceptibility genesSemantic proximity
Germline Variants in 32 Cancer-Related Genes among 700 Chinese Breast Cancer Patients by Next-Generation Sequencing: A Clinic-Based, Observational Study.Semantic proximity
The spectrum of BRCA mutations and characteristics of BRCA-associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next-generation sequencing.Semantic proximity
Germline Mutation in 1338 BRCA-Negative Chinese Hereditary Breast and/or Ovarian Cancer Patients: Clinical Testing with a Multigene Test Panel.Semantic proximity
Germline mutations in 40 cancer susceptibility genes among Chinese patients with high hereditary risk breast cancer.Semantic proximity
Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing SuggestionsSemantic proximity
Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individualsSemantic proximity
Identification of a comprehensive spectrum of genetic factors for hereditary breast cancer in a Chinese population by next-generation sequencing.Semantic proximity
Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test.Semantic proximity
What is the appropriate genetic testing criteria for breast cancer in the Chinese population?-Analysis of genetic and clinical features from a single cancer center database.Semantic proximity
Prevalence and clinical significance of germline pathogenic variants identified by multigene panel testing in high-risk Japanese patients with breast cancer.Semantic proximity
Select a neighboring publication to make it the new centre.